Felis ISSN 2398-2950

Hemangiosarcoma

Contributor(s): Serena Brownlie, Phil Fox, Philip K Nicholls, Penny Watson

Introduction

  • Uncommon in cat, can be dermal or visceral (liver/splenic), although dermal is more frequently reported.
  • Cause: malignant tumor of endothelial cells.
  • Signs: firm/fluctuant nodule dermis/subcutaneous, usually single although may be multiple. Can occur anywhere on skin, but more common on extremities.
  • Splenic/liver   →   collapse, abdominal distention.
  • Diagnosis: dermal - biopsy/fine needle aspirate cytology usually only show non-clotting blood, rarely are neoplastic cells seen.
  • Treatment: surgery +/- chemotherapy Chemotherapy; general principles.
  • Prognosis: dermal - good to guarded; visceral - poor.

Pathogenesis

Pathophysiology

  • Dermal tumors usually isolated, but can be multiple.
  • Must rule out metastases from other sites, eg splenic.
  • More often located on extremities.
  • Splenic - very malignant, metastasize to liver and other sites, biological behavior similar to canine splenic hemangiosarcoma.
  • Dermal - locally recurrent; can metastasize, often pulmonary, less aggressive than splenic.

Timecourse

  • Months:
    • Skin tumors more likely to be noticed earlier.
    • Splenic, only when severe clinical signs are apparent, eg anemia.

Diagnosis

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Treatment

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Outcomes

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Further Reading

Publications

Refereed papers

  • Recent references from PubMed and VetMedResource.
  • Merlo M, Bo S & Ratto A (2002) Primary right atrium haemangiosarcoma in a cat. J Feline Med Surg (1), 61-64 PubMed.
  • Scavelli T D, Patnaik A K, Mehlhaff C J et al (1985) Haemangiosarcoma in the cat - retrospective evaluation of 31 surgical cases. JAVMA 187 (8), 817-819 PubMed.
  • Patnaik A K & Liu S K (1977) Angiosarcoma in cats. JSAP 18 (3), 191-198 PubMed.

Other sources of information

  • Small Animal Clinical Oncology: Withrow and MacEwen.
  • Vet Clinics North America: Radiation Oncology.


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