Equis ISSN 2398-2977

Neomycin

Synonym(s): Neomycin sulfate

Contributor(s): Sally Anne Argyle

Introduction

Name

  • Neomycin Sulfate.

Class of drug

  • Aminoglycoside antibacterial.

Description

Physical properties

  • Tablets.
  • Suspension/sterile aqueous suspension.
  • Pale yellow oily suspension.
  • Cream.

Storage requirements

  • Tablets:
    • <25°C.
    • In a tightly closed container.
  • Suspension:
    • Refrigerate between 2-8°C.
    • Protect from light.
    • Do not freeze.
  • Oily suspension/cream:
    • <25°C.
    • Do not store in fridge.
    • Protect from light.

Uses

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Indications

  • Neomycin-sensitive infections.
  • Gram-negative infections.
  • Some Gram-positive organisms not streptococci   Streptococcus spp  .
  • Hepatic encephalopathy.

Unauthorized in the UK for hepatic encephalopathy.

Administration

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Pharmacokinetics

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Precautions

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Interactions

with other drugs

  • Synergistic with beta-lactam antibacterials.
  • Phenoxymethylpenicillin: reduced penicillin absorption.
  • Warfarin: enhanced anticoagulant effect.

Adverse Reactions

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Further Reading

Publications

Refereed papers

Other sources of information

  • Derived from The Veterinary Formulary (2004) 6th edn. Ed: Bishop Y. British Veterinary Association and Royal Pharmaceutical Society. ISBN: 0853695792.

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