Milbemycin oxime

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Sections available in full article Name, Class of drug, Description, Uses, Administration, Routes of administration, Dosage, Pharmocokinetics, Normal, Physiological, variations, Precautions, Use with care, Adverse reactions, Sources, Publications,
Contributors

Name

  • Milbemycin.

Class of drug

  • Macrolide lactone.

Uses

Action

  • Opens chloride channels in parasite post-synaptic membrane.

Indications

  • Preventative treatment for heartworm in dogs and to prevent dirofilaria larval infection in cats.
  • Effective against:
    • Ancylostoma caninum .
    • Toxocara canis .
    • Trichuris vulpis .
    • Demodex .
    • Toxocara cati  Toxocara cati  .
    • Ancylostoma tubaeforme .
    • Toxascaris leonina .

Adverse reactions

Effects of overdosage

  • High safety margin of up to 20 times the recommended dose.
  • Ataxia.
  • Pyrexia.
  • Weakness.
  • Salivation.
  • Signs related to worm kill.

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