Triamcinolone

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Sections available in full article Name, Class of drug, Uses, Administration, Routes of administration, Dosage, Pharmocokinetics, Physiological, variations, Pathological variations, Precautions, Contra-indications, Interactions, Adverse reactions, Sources, Publications,
Contributors

Name

  • Triamcinolone acetonide.

Class of drug

  • Glucocorticoid.

Uses

Action

  • Triamcinolone is an intermediate-acting glucocorticoid, which has approximately 1.25 times the anti-inflammatory potency of prednisolone  Prednisolone  . On a dose basis 0.8 mg triamcinolone is equivalent to 1 mg prednisolone.
  • Has negligible mineralocorticoid activity.

Indications

  • Used in the management of inflammatory arthritides  Degenerative joint disease  and dermatoses .
  • Unsuitable for alternate day use because of its duration of activity.

Adverse reactions

Other reported reactions

  • Gastrointestinal ulceration (increased risk of gastrointestinal ulceration if NSAIDs used concurrently).
  • Elevated liver enzymes.
  • Weight loss.
  • Polyuria/polydipsia.
  • Vomiting and diarrhea.
  • Chronic use may lead to the development of iatrogenic hyperadrenocorticalism.
  • Delayed wound healing and immunosuppression.
  • A single injection may suppress adrenal gland function for up to 4 weeks.

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