Megestrol acetate

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Sections available in full article Name, Class of drug, Uses, Administration, Routes of administration, Dosage, Precautions, Contra-indications, Use with care, Adverse reactions, Sources, Publications, Vetstream contributor(s),
Contributors Dr Rosanna Marsella DVM DipACVD

Name

  • Megestrol acetate.

Class of drug

  • Oral progestagen.

Uses

Indications

  • Prevention and postponement of estrus in the bitch and queen.
  • Pseudopregnancy  Pseudopregnancy  .
  • Estrogen-dependent mammary tumors  Mammary gland: neoplasia  in the bitch.
  • Behavioral problems in the male dog.
  • Miliary dermatitis  Dermatitis: miliary  and eosinophilic granuloma  Eosinophilic granuloma complex  in the cat.

Adverse reactions

Other reported reactions

Dog
  • Temperament change (listlessness).
  • Increased thirst or appetite.
  • Cystic endometrial hyperplasia/pyometra.
  • Diabetes mellitus.
  • Adrenocortical suppression.
  • Mammary enlargement/neoplasia and lactation.
  • As progestogens may cause elevated levels of growth hormone in the dog, acromegaly may develop.

Cat

  • Personality changes.
  • Increased thirst or appetite.
  • Adrenocortical suppression.
  • Mammary hyperplasia or adenocarcinoma, diabetes mellitus and pyometra.

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