Chlorambucil

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Sections available in full article Name, Class of drug, Description, Uses, Administration, Routes of administration, Dosage, Pharmocokinetics, Normal, Precautions, Use with care, Interactions, Adverse reactions, Sources, Publications, Vetstream contributor(s),
Contributors Dr William Brewer Jr DVM DiplACVIM Oncology and Internal Medicine
Dr Laura Garrett DVM DACVIM (Oncology)

Name

  • Chlorambucil.

Class of drug

  • Antineoplastic cytotoxic immunosuppressive alkylating agent.

Uses

Action

  • Nitrogen mustard type bifunctional alkylating agent.

Indications

  • Lymphoproliferative  Lymphoma  , myeloproliferative and immune-mediated diseases  Anemia: immune-mediated hemolytic  .
  • Substitue for cyclophosphamide in lymphoma protocols.

Adverse reactions

Other reported reactions

  • Anorexia (rare).
  • Nausea (rare).  
  • Vomiting (rare).
  • Leukopenia (mild to moderate - may be prolonged).
  • Thrombocytopenia (uncommon).
  • Anemia (rare).

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