Sedation or sedative protocol

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Sections available in full article Introduction ,  Acepromazine ,  Benzodiazepines ,  Opioids ,  Alpha-2 agonists ,  Ketamine ,  Sources, Publications, Vetstream contributor(s),
Introduction ,  Acepromazine ,  Benzodiazepines ,  Opioids ,  Alpha-2 agonists ,  Ketamine ,  Sources,
Contributors Dr John Dodam DVM MS PhD DipACVA
Dr Jo Murrell BVSc(Hons) PhD DipECVAA MRCVS

Introduction

Indications for sedation

  • To reduce stress and anxiety.
  • Improve animal welfare.
  • Reduce risk of catecholamine-induced dysrhythmias  Heart: dysrhythmia  .
  • Reduce risk of handling difficult cats.
  • To enable a thorough clinical examination.
  • To perform diagnostic procedures.
  • To perform minor surgical procedures.
  • As premedication prior to general anesthesia  General anesthesia: overview  .

General rules

  • Allow adequate time for onset of action of the sedative after administration.
  • During this time it is very important to keep the cat in a quiet environment to get maximum sedative effect.
    Always monitor a cat that has been sedated.
  • IV administration generally produces the greatest sedative effect in the shortest time.
  • The time to peak sedation is longer after IM or SC administration, but the effect generally lasts longer.
  • Depressive effects on the CNS may be additive or synergistic with other agents.
  • Cats are particularly sensitive to hypothermia  Hypothermia   when sedated.
  • Weigh animal on scales - do not guess weight.
  • Combining sedatives often enhances potency while minimizing side effects.

Sedative agents

  • These include:
    • Acepromazine.
    • Benzodiazepines.
    • Opioids.
    • Alpha-2 agonists.
    • Ketamine.

Sources

Publications

Refereed papers


  • Recent references from PubMed .
  • Dyson D H (2008) Analgesia and chemical restraint for the emergent veterinary patient. Vet Clin North Am Small Anim Pract 38 , 1329-1352 PubMed .
  • Lemke K A (2004) Perioperative use of selective alpha-2 agonists and antagonists in small animals. Can Vet J 45 , 475-480 PubMed .
  • Vaha-Vahe T (1989) Clinical evaluation of medetomidine, a novel sedative and analgesic drug for dogs and cats. Acta Vet Scand 30 (3), 267-273.

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