Therapeutics: non-bacterial infection

Antifungal agents

* Indicates product not licensed for this use in this species.

Topical agents

• Treatment of fungal infections of skin, ear and eye.

Skin infections

• Successful treatment depends on management which limits infection, eg grooming, clipping, isolation, cleansing agents for animal and environment.
• Systemic agents may be used also.
• Dermatophytoses :    commonly caused by Trichophyton spp    and Microsporum    :
  • Enilconazole *    wash.
• Pruritic skin disease , eg seborrhea    and otitis externa    caused by Malassezia pachydermatis :
  • Enilconazole *    wash.
  • Ketoconazole *    shampoo.
  • Miconazole *    Chlorhexidine *    shampoo.
• Others :
  • Povidone-iodine    solution.

Ear infections

• Usually combination preparations.
• Yeasts :
  • Nystatin *    .
  • Miconazole *    .
  • Tiabendazole *    .

Eye infections

• Conditions may be superficial, eg mycotic keratitis    or intra-ocular, eg mycotic endophthalmitis.
• Most topical preparations have poor corneal penetration, so systemic preparations preferred.

Aspergillosis

• For systemic disease     (rare in cats).
• Aspergillus fumigatus    : treatment with systemic ketoconazole *    .

Sources

Publications

Refereed papers

• Recent references from PubMed .

Other sources of information

• Lappin M R (2000) Protozoal and miscellaneous infections. In: Textbook of Veterinary Internal Medicine. 5th edn. Ettinger S J & Feldman E C (eds). W B Saunders, Philadelphia. pp 408-417.
• Taboada J (2000) Systemic mycoses. In: Textbook of Veterinary Internal Medicine. 5th edn. Ettinger S J & Feldman E C (eds). W B Saunders, Philadelphia. pp 453-476.
• Plumb D C (1999) Veterinary Drug Handbook. 3rd edn. Iowa State University Press, Ames, Iowa.