Ventricular premature contraction

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Sections available in full article Introduction, Presenting signs, Acute presentation, Pathogenesis, Etiology, Predisposing factors, Pathophysiology, Timecourse (incubation, duration), Diagnosis, Client history, Clinical signs, Diagnostic investigation, Confirmation of diagnosis, Gross autopsy findings, Histopathology findings, Differential diagnosis, Treatment, Initial symptomatic treatment, Standard treatment, Monitoring, Sequelae, Prognosis, Expected response to treatment, Reasons for treatment failure, Sources, Vetstream contributor(s),
Contributors Dr Phil Fox DVM DipACVIM DipECVIM ACVECC
Dr Philip K Nicholls BVSc BSc PhD MRCVS FRCPath
Synonyms VPC

Introduction

  • Cause : usually myocardial irritation due to primary cardiac or systemic disease.
  • Signs : depends on frequency - may be asymptomatic or weakness and lethargy.
  • Diagnosis : electrocardiography.
  • Treatment : treat underlying disease, antidysrhythmic agents if required.
  • Prognosis : variable - occasional VPCs do not effect mortality. Guarded related to significant underlying pathology.

Diagnosis

Clinical signs

  • Irregular heart beat.
  • VPCs may be linked to normal beat so may regularly hear irregular sounds, ie double beat followed by compensatory pause.
  • Pulse rate does not match heart rate (pulse deficit).
  • Evidence of poor peripheral perfusion, eg pallor.
  • Signs of underlying disease, eg murmur.

Diagnosis

Differential diagnosis

  • Atrial premature contraction with abnormal ventricular conduction.
  • Bundle branch block.
  • Ventricular escape complexes.

Sequelae

Prognosis

  • Depends on underlying disease - if this can be controlled dysrhythmia may resolve spontaneously.
  • Electrically unstable VPCs may progress to ventricular tachycardia which carries a guarded prognosis.

Expected response to treatment

  • Reduced frequency of VPCs on electrocardiogram.
  • Improving demeanor of patient.

Reasons for treatment failure

  • Severe underlying pathology.
  • Failure to recognize and treat progressing VPCs before ventricular tachycardia  Ventricular tachycardia  develops.

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