Eosinophilic plaque

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Sections available in full article Introduction, Presenting signs, Sex predisposition, Pathogenesis, Etiology, Pathophysiology, Diagnosis, Presenting problems, Client history, Clinical signs, Diagnostic investigation, Confirmation of diagnosis, Differential diagnosis, Treatment, Initial symptomatic treatment, Standard treatment, Monitoring, Sequelae, Prognosis, Expected response to treatment, Sources, Publications, Vetstream contributor(s),
Contributors Dr Rosanna Marsella DVM DipACVD
Mr David Scarff BVetMed CertSAD MRCVS

Introduction

  • Cause : various hypersensitivity disorders or heritable.
  • Signs : erythematous, raised, exudative lesions anywhere on the body including oral cavity.
  • Diagnosis : history and clinical signs.
  • Treatment : identification and correction of underlying cause. Symptomatic.
  • Prognosis : excellent if underlying disorder is identified and treated.

Diagnosis

Clinical signs

  • Focal area of intense pruritus.
  • Erythematous, well-circumscribed, raised lesions which are oozing and ulcerated. Round to oval 0.5-7cm in diameter.
  • Particularly ventral abdomen and medial thighs  Linear granuloma  though anywhere on the skin or mucocutaneous junctions. Also on oral cavity.
  • Ulcerated or crusted with a cobblestone appearance to the surface.
  • Peripheral lymphadenopathy is common.

Diagnosis

Differential diagnosis

  • Bacterial granuloma  Bacterial skin disease: overview  .
  • Fungal granuloma .
  • Neoplasia, eg squamous cell carcinoma  Squamous cell carcinoma  , mast cell tumor  Mastocytoma  , or lymphosarcoma  Lymphoma  .

Sequelae

Prognosis

  • Variable dependent on whether an underlying cause has been found and corrected.
  • Long term symptomatic management usually required in cases where the underlying cause cannot be identified.

Expected response to treatment

  • Improvement over 3-6 weeks with treatment.

Sources

Publications

Refereed papers

  • Kimura Tet al(2003)Expression of RANTES mRNA in skin lesions of feline eosinophilic plaque.Vet Dermatol.14(5), 269-273.DOI
  • Scarampella F, Abramo F & Noli C (2001)Clinical and histological evaluation of an analogue of palmitoylethanolamide 120 (comicronized Palmidrol INN) in cats with eosinophilic granuloma and eosinophilic plaque - a pilot study.Vet Dermatol12(1), 29-39.
  • Power H Tet al(1995)Selected feline eosinophilic skin diseases.Vet Clin North Am Small Anim Pract25(4), 833-850.
  • Moriello K Aet al(1990)Lack of autologous tissue transmission of eosinophilic plaques in cats.Am J Vet Res51(7), 995-998.

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