Feline calicivirus

Buy now to access the full article, existing subscribers login

Sections available in full article Classification, Distribution, Significance, Active Forms, Active Form 1, Clinical Effects, Epidemiology, Pathological effects, Other Host Effects, Control, Diagnosis, Useful samples, Specimen storage, Transport of samples, Isolation, Field diagnosis, Laboratory diagnosis, Sources, Publications, Vetstream contributor(s), Organization(s),
Contributors Dr Susan Dawson BVMS PhD MRCVS
Dr Alan Radford BSc BVSc PhD MRCVS
Dr Melissa Kennedy DVM PhD DipACVM
Dr Karen Coyne BSc(Hons) PhD
Synonyms FCV, picornavirus, cat flu virus, Manx virus

Classification


Taxonomy

  • Family: caliciviruses .

Etymology

  • Greek: calyx means cup, calicivirus has many cup-shaped subunits on its surface as seen by electronmicroscopy.

Distribution

  • Worldwide.
  • FCV is ubiquitous and high prevalence is seen in cats with non oral/respiratory disease. Prevalence is generally proportional to number of cats within a household group, with highest prevalences usually seen where large numbers of cats are housed together:
    • Vet visiting cat population prevalence ~10%.
    • Cats at cat shows in the UK ~25%.
    • Cats living in large groups or rescue shelters ~25-40%; in some instances prevalence in large groups has been reported up to ~90% persisting for prolonged periods of time.

Significance

In cats
  • Significant cause of cat flu  Viral-induced upper respiratory tract disease  (upper respiratory tract infection).
  • Characteristic lesions are oral ulcerations.
  • Isolated from a high percentage of cats with chronic stomatitis.
  • Chronic gingivitis  Gingivitis and stomatitis  .
  • Rarer cause of shifting lameness.
  • Inapparent infections and pneumonia may also be seen with FCV infection.
  • Recently associated with a virulent systemic disease (FCV associated VSD).

Other species

  • Does not affect non-felidae, although FCV-like viruses have been isolated from dogs; other species have their own caliciviruses.

Sources

Publications

  • Recent references fromPubMed.
  • Porter C J, Radford A D, Gaskell R M, Ryvar R, Coyne K P, Pinchbeck G L, Dawson S (2008)Comparison of the ability of feline calicivirus (FCV) vaccines to neutralise a panel of current UK FCV isolates.J Feline Med Surg10(1), 32-40PubMed.
  • Radford A D, Coyne K P, Dawson S, Porter C J, Gaskell R M (2007)Feline calicivirus.Vet Res38(2), 319-35PubMed.
  • Coyne K P, Dawson S, Radford A D, Cripps P J, Porter C J, McCracken C M, Gaskell R M (2006)Long-term analysis of feline calicivirus prevalence and viral shedding patterns in naturally infected colonies of domestic cats.Vet Microbiol118(1-2),12-25PubMed.
  • Coyne K P, Jones B R, Kipar A, Chantrey J, Porter C J, Barber P J, Dawson S, Gaskell R M, Radford A D (2006)Lethal outbreak of disease associated with feline calicivirus infection in cats.Vet Rec158(16), 544-550PubMed.
  • Schorr-Evans EM, Poland A, Johnson WE & Pedersen NC (2003)An epizootic of highly virulent feline calicivirus disease in a hospital setting in New England. J Feline Med Surg5(4), 217-226PubMed.
  • Radford ADet al(2001)Molecular analysis of isolates of feline calicivirus from a population of cats in a rescue shelter.Vet Rec149(16), 477-481
  • Dawson S, Willoughby K, Gaskell R Met al(2001)A field trail to assess the effect of vaccination against feline herpesvirus, feline calicivirus and feline panleucopenia virus in 6-week old kittens.JFMS3, 17-22.
  • Binns S H, Dawson S, Speakman A J, Cuevas L Eet al(2000)A study of feline upper respiratory tract disease with reference to prevalence and risk factors for infection with feline calicivirus and feline herpesvirus.JFMS2, 123-133.
  • Radford A D, Dawson S, Wharmby C, Ryvar R & Gaskell R M (2000)Comparison of serological and sequence based methods for typing feline calicivirus isolates from vaccine failures.Vet Rec146, 117-123.
  • Radford A Det al(1999)Quasispecies evolution of a hypervariable region of the feline calicivirus capsid gene in cell culture and persistently infected cats.Vet Microbiol69(1-2), 67-68.
  • Thiel H Jet al(1999)Caliciviruses - an overview.Vet Microbiol69(1-2), 55-62.
  • Vuuren van M, Geissler K, Gerber D, Nothling J O & Truyen U (1999)Characterisation of a potentially abortigenic strain of feline calicivirus isolated from a domestic cat.Vet Rec144, 636-638.
  • Dawson S & Willoughby K (1999)Feline infectious upper respiratory tract disease - an update.In Practice5, 232-252.
  • Dawson S, Gaskell R & Jarrett O S (1999)Vaccination in cats - an update.In Pract21, 71-74.

Sample content only, to unlock the full article login or buy now

Loading...