Lomustine

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Sections available in full article Name, Class of drug, Description, Uses, Administration, Routes of administration, Dosage, Timing of administration, Pharmocokinetics, Normal, Pathological variations, Precautions, Use with care, Sources, Publications,
Contributors Dr William Brewer Jr DVM DiplACVIM Oncology and Internal Medicine
Synonyms CeeNU, CCNU

Name

  • Lomustine.

Class of drug

  • Alkylating agent in the nitrosurea family.

Uses

Action

  • Acts as an alkylating agent. May also inhibit several key enzymatic processes.

Indications

  • Granulomatous meningioencephalitis (GME Granulomatous meningoencephalomyelitis ), other inflammatory CNS diseases.
  • Indicated as a single agent or as part of combination therapy in the treatment of high grade or metastatic mast cell tumors Skin: mastocytoma , epitheliotropic or refractory lymphoma Lymphoma and multiple myeloma Myeloma.

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