Clomipramine hydrochloride

Name

• Clomipramine.

Class of drug

• Tricyclic antidepressant.

Uses

Action

• Blocks serotonin and norepinephrine re-uptake in the brain, effectively increasing their effects.

Indications

• May be useful in the management of obsessive-compulsive canine behaviours such as tail chasing, fly biting, flank sucking, licking associated with lick granulomas .
• Separation anxiety in dogs.
• Elimination problems in cats.
• It should be used in combination with behavioural therapy for separation related disorders manifested by destruction and inappropriate urination and defecation.

Adverse reactions

Other reported reactions

• In man various side effects are described, including sedation, dry mouth, diarrhea, excitability, arrhythmias, hypotension, syncope, weight gain and, much less commonly, seizures and bone marrow disorders.

• Sporadic vomiting.
• Changes in appetite.
• Lethargy.