Name
- Ticarcillin.
Class of drug
- Carboxypenicillin antibiotic.
Uses
Action
- Member of the beta-lactam group of antibiotics.
- Binds to penicillin-binding proteins near bacterial cell walls, thereby decreasing bacterial cell wall strength and rigidity, affecting cell division, growth and septum formation.
- Susceptible to beta-lactamase enzymes but is co-formulated with clavulanic acid, the beta lactamase inhibitor.
Indications
- Principally indicated for the treatment of serious (usually but not exclusively life threatening) Pseudomonas aeruginosa
infections. - For pseudomonas septicaemias ticarillin should be given with an aminoglycoside, eg gentamicin .
- Activity against certain other gram-negative bacilli including Proteusspp and Bacteroides fragilis
.
