Betamethasone
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Uses
Indications
- Anti-inflammatory - potency 8.75 times greater than prednisolone.
- May have role in management of shock
.
Adverse reactions
Other reported reactions
- Prolonged use of glucocorticoids will suppress the hypothalamic-pituitary axis (HPA) and cause adrenal atrophy.
- Weight loss and cutaneous atrophy (catabolic effect).
- Signs of iatrogenic hyperadrenocorticism may develop (PU/PD, elevated liver enzymes).
- Vomiting and diarrhea (with gastrointestinal ulceration in some cases).
- May increase urine glucose levels and decrease serum T3 and T4 values.
- Impaired wound healing and delayed recovery from infection may be seen.
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