Amoxicillin
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Uses
Action
- Bacteriocidal antibiotic.
- Acts by binding to penicillin-binding proteins near bacterial cell walls, thereby decreasing bacterial cell wall strength and rigidity, and affecting cell division, growth and septum formation.
- As mammalian cells lack a cell wall, the beta-lactam antibiotics are extremely safe.
Indications
- Active against certain gram-positive and negative organisms.
- Not active against those that produce penicillinases, eg E. coli
and Staphylococcus aureus
.
- The more difficult gram-negative organisms ( Pseudomonas spp
and Klebsiella spp) are usually resistant.
Adverse reactions
Other reported reactions
- Nausea.
- Diarrhea.
- Skin rashes.
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