Ureter: neoplasia

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Introduction

  • Very rare cause of intramural obstruction; only 16 cases of primary ureteral neoplasia reported.
    • May be involvement with other tumor, eg lymphoma or intestinal carcinoma, rather than primary.
  • Most frequently ureteral tumors are local extension from a bladder tumor (usually transitional cell carcinoma) into the ureters.

Diagnosis

Clinical signs

  • Physical examination non-specific.
  • Abdominal pain.
  • Cranial to mid-abdominal mass.

Outcomes

Prognosis

  • Depends on tumor type.
  • Benign lesions can be cured.
  • Malignant tumors have variable reported prognoses, with a range of 5 months to >2 years with surgery.

Reasons for treatment failure

  • Metastatic disease occurrence.
  • Local regrowth if mass is invasive into musculature.
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