Retinal dysplasia

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Sections available in full article Introduction, Presenting signs, Age predisposition, Sex predisposition, Breed predisposition, Pathogenesis, Pathophysiology, Diagnosis, Presenting problems, Client history, Clinical signs, Diagnostic investigation, Confirmation of diagnosis, Differential diagnosis, Treatment, Subsequent management, Sequelae, Prognosis, Sources, Publications, Vetstream contributor(s),
Contributors Dr Rhea Morgan DVM DACVIM DACVO

Introduction

  • Abnormal development and growth of the retina resulting in retinal folds, rosettes and sometimes retinal detachment Retina: detachment.
  • Cause: inherited in many dogs, acquired forms develop from insults experienced in utero or soon after birth.
  • Signs: no clinical signs with mild forms; blindness Blindness with severe forms; one form is accompanied by skeletal chondrodysplasia.
  • Diagnosis: signs, ophthalmoscopic examination.

Diagnosis

Clinical signs


Multifocal, geographic dysplasia

  • Retinal folds, rosettes or detachment observed on ophthalmoscopic examination.
  • Possible cataracts
  • Possible hyaloid remnants (uncommon)

Total dysplasia

  • Blindness.
  • Dilated pupils.
  • Abnormal pupillary light reflexes.
  • Cataract.
  • Hyaloid remnants.
  • Skeletal dwarfism.
  • Absence of anterior chamber.
  • Other ocular defects.

Diagnosis

Differential diagnosis

  • Physiologic folds in the retina of dogs less than 4 months old, due to a disparity in growth between the inner and outer optic cups.
  • Post-inflammatory retinal detachment.
  • Quiescent chorioretinal scarring.

Sequelae

Prognosis

  • Prognosis for vision in dogs with multifocal disease is good.
  • Prognosis for vision in dogs with geographic lesions depends upon the amount of retina affected, and whether cataract formation also occurs.
  • Dogs with skeletal chondrodysplasia are frequently blind from retinal detachments by 6 months of age.

Sources

Publications

Refereed papers

  • Long S E, Crsip S M (1999) Inheritance of multifocal retinal dysplasia in the golden retriever in the UK. Vet Rec 145, 702-704.
  • Holle D M, Stankovics M E, Sarna C R et al(1999) The geographic form of retinal dysplasia in dogs is not always a congenital abnormality. Vet Comp Ophthalmol 2 , 61-66.
  • Carrig C B, Sponenberg U P, Schmidt G M et al(1988) Inheritance of associated ocular and skeletal dysplasia in Labrador retrievers. J Am Vet Med Assoc 193 , 1269, 1998.
  • Myers V N, Jesyk G D, Aguirre G et al(1983) Short-limbed dwarfism and ocular defects in the Samoyed dog. J Am Vet Med Assoc 183, 975.
  • Carrig C D, MacMillan A, Brundage S et al(1977) Retinal dysplasia associated with skeletal abnormalities in Labrador retrievers. J Am Vet Med Assoc 170 ,49.

Other sources of information

  • Wheeler CA (1997) Disorders of the posterior segment. In: Morgan RV (ed): Handbook of Small Animal Practice.3rd Ed. W B Saunders, Philadelphia, pp 1047-1058.

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