Lens: congenital primary cataract

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Sections available in full article Introduction, Presenting signs, Age predisposition, Breed predisposition, Cost considerations, Pathogenesis, Etiology, Predisposing factors, Pathophysiology, Timecourse (incubation, duration), Diagnosis, Client history, Clinical signs, Diagnostic investigation, Confirmation of diagnosis, Histopathology findings, Treatment, Initial symptomatic treatment, Standard treatment, Monitoring, Prevention, Control, Sequelae, Prognosis, Expected response to treatment, Reasons for treatment failure, Sources, Publications, Vetstream contributor(s),
Contributors Dr Dennis E Brooks DVM PhD DipACVO
Dr David L Williams MA VetMB PhD CertVOphthal FRCVS

Introduction

  • A cataract is an opacification of the lens.
  • May be primary (breed-related) or secondary due to disease (uveitis, diabetes, PRA).
  • Developmentally staged as incipient, immature (tapetal reflex present), mature (no tapetal reflex/blindness) and hypermature (wrinkled lens capsule).
  • Either congenital, eg Miniature Schnauzer, Boston Terrier, Welsh Springer Spaniel, at early age, eg Afghan Hound, German Shepherd dog or at later stage, eg Standard Poodle.
  • Usually inherited (autosomal recessive).
  • Inherited as incomplete dominant in Labrador Retriever, Golden Retriever (posterior subcapsular opacity).
  • Good prognosis if phacoemulsification performed and if no other ocular structures involved.
  • Early developing cataract: remove at an early stage either by irrigation, aspiration, extracapsular extraction or phacoemulsification → prevents lens-induced uveitis.

Diagnosis

Clinical signs

  • Lens opacification.
  • May be uveitis in some cases, eg aqueous flare, miosis.
  • Slit lamp exam to localize opacity.
  • Ophthalmoscopy - unable to see fundus in mature cataracts.

Sequelae

Prognosis

  • Cataracts that progress to maturity can produce uveitis, secondary glaucoma and retinal detachment.

Expected response to treatment

  • Vision is present.

Reasons for treatment failure

  • Post-operative glaucoma.
  • Post-operative retinal detachment.
  • Post-operative ophthalmitis.
  • Poor compliance with medical therapy after surgery.

Sources

Publications

Refereed papers

  • Gelatt K N (1998) Veterinary Ophthalmology. 3rd edn. Williams & Wilkins.
  • Williams D L, Boydell I P & Long R D (1996) Current concepts in the management of canine cataract: a survey of techniques used by surgeons in Britain, Europe and the USA and a review of recent literature. Vet Rec 138 (15), 347-53.

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