Lens luxation

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Sections available in full article Introduction, Presenting signs, Acute presentation, Age predisposition, Breed predisposition, Cost considerations, Pathogenesis, Etiology, Predisposing factors, Pathophysiology, Timecourse (incubation, duration), Diagnosis, Presenting problems, Client history, Clinical signs, Diagnostic investigation, Confirmation of diagnosis, Histopathology findings, Differential diagnosis, Treatment, Initial symptomatic treatment, Standard treatment, Sequelae, Prognosis, Reasons for treatment failure, Sources, Publications, Vetstream contributor(s),
Contributors Dr Dennis E Brooks DVM PhD DipACVO
Dr David L Williams MA VetMB PhD CertVOphthal FRCVS

Introduction

  • Primary luxation occurs in the absence of other ocular disease and results from degeneration of the zonule.
  • Cause : inherited in several breeds.
  • Secondary luxation occurs as a result of other ocular disease, eg glaucoma, where stretching of the scleral tunics results in rupture of the zonule.
  • Signs : corneal opacity, glaucomatous eye.
  • Diagnosis : clinical examination.
  • Treatment : treated as emergency because can increase intra-ocular pressure and result in irreversible vision loss.

Diagnosis

Clinical signs

  • Glaucoma.
  • Aphakic crescent if lens is subluxated.
  • Iridodonesis - iris 'wobble' with eye movements because lens no longer supports iris.
  • Vitreal material in anterior chamber.
  • Deep anterior chamber if posterior luxation.
  • Lens visible in anterior chamber.

Diagnosis

Differential diagnosis

  • Uveitis Uveitis.
  • Glaucoma Glaucoma.
  • Ulcer Persistent corneal erosions.
  • Endothelial dystrophy.

Sequelae

Prognosis

  • Good prognosis for saving vision following lendectomy in early cases of primary disease in dogs.
  • Fair chance glaucoma will develop before or lens luxation following lendectomy.
  • Monitor IOP, pain, condition of other eye.

Reasons for treatment failure

  • Retinal detachment.
  • Glaucoma.

Sources

Publications

Refereed papers

  • Curtis R (1990) Primary lens luxation in the dog and cat. Vet Clin North Am 20 (3), 755-773.
  • Curtis R (1983) The mechanics of lens dislocation in the dog. Vet Ann 23 , 191-195.
  • Gwin R M (1982) Primary lens luxation in the dog associated with lenticular zonule degeneration and its relationship to glaucoma. JAAHA 18 , 485-489.

Other sources of information

  • Gelatt K N (1999) Veterinary Ophthamology. 3rd edn. Lippincott, Williams & Wilkins.

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