Skin: pemphigus erythematosus
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Introduction
- Rare benign focal form of pemphigus foliaceus
, shares some features of discoid lupus erythematosus
.
- Cause : varied.
- Signs : erythema, pustular dermatitis on face ( periocular, junction of nasal planum to haired skin, occasionally lip margins) and ears, nasal depigmentation.
- Diagnosis : history, clinical signs, histopathology.
- Treatment : immunosuppressive chemotherapy.
- Prognosis : good.
Diagnosis
Clinical signs
- Erythematous, pustular dermatitis, or crusting lesions on face and ears.
- Nasal depigmentation → photo-aggravation of disease.
- Scales, crusts and erosions.
- No systemic illness.
- Variable pain and pruritus.
- Involvement of paws, footpads, and genitalia (rarely).
- Epidermal fragility (Nikolsky sign) may be present.
Diagnosis
Differential diagnosis
- Bacterial folliculitis
.
- Dermatophytosis
.
- Demodicosis
.
- Lupus erythematosus (discoid
) (systemic
).
- Seborrhea
.
- Dermatomyositis
.
- Drug eruption
.
- Subcorneal pustular dermatosis.
- Zinc-responsive dermatosis
.
- Cutaneous lymphoma (epitheliotropic)
.
- Eosinophilic furunculosis
.
- Pemphigus foliaceus
.
Sources
Publications
Refereed papers
- White S D, Rosychuk R A, Reinke S I et al(1992) Use of tetracycline and niacinamide for treatment of autoimmune skin disease in 31 dogs.
JAVMA
220 , 1497-1500.
- Carloti D (1989) Autoimmunemediated skin disease.
JSAP
30 , 223-227.
- Carlotti D (1989) Proceedings of 1987 symposium on skin disease at Lanwade Hall, Newmarket
JSAP
30 , 223-227 (Illustrated with color photos).
- Johnson B W & Campbell K L (1989) Dermatoses of the canine eyelid.
Comp Cont Ed Pract Vet
11 , 385-394.
- Griffin C E (1987) Diagnosis and management of primary auto-immune skin diseases - a review.
Seminars in Veterinary Medicine and Surgery
2 , 173-185.
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