- Rare conditions with abnormal proteinaceous deposits within tissues.
- Cause : familial disease in Abyssinians or Siamese or secondary to chronic inflammation.
- Signs : related to organ affected. May be localized or systemic.
- Diagnosis : histopathology, special staining and immunohistochemistry.
- Treatment : few options.
- Prognosis : guarded, usually progressive.
- Kidneys small and irregular (chronic stage).
- Dyspnea (if pulmonary thrombosis).
- Hindleg paralysis (if aortic thrombosis).
- Other causes of chronic renal failure .
- Thromboembolism due to cardiomyopathy.
- Poor: usually progressive deposition.
Expected response to treatment
- Improvement in clinical signs.
- Lack of progression of disease.
Reasons for treatment failure
- Disease usually progressive.
- Presence of underlying chronic renal failure.